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Oral Disintegrating Products

Orally disintegrating tablets (ODT), are an innovative solid oral dosage form that is becoming more and more important in the pharmaceutical market, both for prescription and over-the-counter medications. In contrast to classical tablets, ODTs are specifically designed to disintegrate directly in the patient's mouth. The disintegrated tablet can then be swallowed easily without any resistance. This type of application offers significant advantages in order to overcome certain weaknesses of classical solid oral dosage forms:

Patient compliance is increased due to ODT superior easy way of administration.

Especially for elderly patients and children this opens up a much more convenient medication option.

ODTs are an on-the-go dosage form, which can be taken without water. This is also of importance where only water of questionable quality is available.

BASF offers a comprehensive set of excipients that help you to easily formulate your active ingredient in an effective ODT:

Ludiflash
A co-processed excipient formulation designed to achieve reliable quick disintegration with an outstanding, creamy mouthfeel of your ODT.

Kollidon CL-F and CL-SF
BASF's widely known Kollidon CL tablet disintegrant series offers two grades that are specifically suitable to disintegrate your ODT with the necessary velocity and excellent mouthfeel.

Kollicoat Smartseal 30 D
BASF's latest excipient innovation, Kollicoat Smartseal 30 D is the unique solution to an ODT problem not solved before. When it comes to pellet and particle coating, other products in the market are too tacky to be applied without individual items sticking together. Kollicoat Smartseal 30 D is the first aqueous coating polymer dispersion able to coat pellets and particles effectively, with best-in class taste-masking and moisture protection.

Ludiflash

Ludiflash is a formulation for fast disintegrating solid oral dosage forms.

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Kollidon® CL-F

Crospovidone for use as a tablet disintegrant, especially for small tablets. It can also be used in wet granulation processes, when large amount of granulation liquids are needed.

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Kollidon® CL-SF

Crospovidone for use as a tablet disintegrant. Suitable for fast dispersible tablets as it generates a pleasant feeling in the mouth.

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Kollicoat® Smartseal 30 D

Kollicoat® Smartseal 30 D is an aqueous dispersion of a co-polymer comprising methyl methacrylate (MMA) and diethylaminoethyl methacrylate (DEAEMA) in a ratio of 6:4. It also contains macrogol cetostearylether 20 (~0.6%) and sodium laruyl sulfate (~0.8%) as stabilizers and has a solids content of 30%.

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