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Solubilizers, Solvents & Cosolvents
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1,2-Propylene Glycol Pharma |
| 1,2-Propylene glycol for use as a solvent in injectables
and in soft gelatine capsules. It is also used in other liquid and semi-liquid dosage forms. |
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Cremophor® A 25 |
| Macrogol 25 cetostearyl ether (Ph.Eur.).
Nonionic solubilizer and emulsifier for ointments and creams based on O/W emulsions. |
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Cremophor® A 6 |
| Macrogol 6 cetostearyl ether (Ph.Eur.).
Nonionic solubilizer and emulsifier for ointments and creams based on emulsions.
It is used mainly in O/W emulsions, but it can also be used in W/O preparations. |
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Cremophor® EL |
| Macrogol glycerol ricinoleate 35 (DAC/Ph.Eur.).
Nonionic solubilizer and emulsifier for oral, topical and parenteral preparations. |
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Cremophor® ELP |
| Like Cremophor® EL, Cremophor® ELP is a nonionic
solubilizer produced via a purification process. |
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Cremophor® RH 40 |
| Macrogol-glycerol hydroxystearate 40 (DAB/Ph.Eur.).
Nonionic solubilizer and emulsifier for oral and topical preparations. |
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Kollidon® 12 PF | Kollidon® 17 PF |
| Low-molecular weight povidones, pyrogen-free, for use as a solubilizing agent,
crystallization inhibitor and suspension stabilizer in injectables and ophthalmic products. |
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Lutrol® E 300 | Lutrol® E 400 | Lutrol® E 600 |
| The Lutrol® E grades are liquid polyethylene glycols (macrogols) with different molecular weights, viscosities and applications. The main application is as a solvent for oral, topical and parenteral applications. |
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Lutrol® F 127 |
| Lutrol® F 127 (Poloxamer 407) is used mainly as a gel former,
thickening agent and solubilizer in oral and topical solutions and as a stabilizer in oral and topical suspensions. |
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Lutrol® F 68 |
| Lutrol® F 68 (Poloxamer 188) is used mainly as an emulsifier, solubilizer and
suspension stabilizer in liquid oral, topical and parenteral preparations, as a plasticizer and to increase
the bioavailability of active ingredients in solid preparations. |
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Lµtrol® micro 127 |
| Micronized Lutrol® F 127, mainly used as bioavailability
enhancer in solid oral dosage forms and as a water soluble lubricant. |
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Lµtrol® micro 68 |
| Micronized Lutrol® F 68, mainly used as bioavailability
enhancer in solid oral dosage forms and as a water soluble lubricant. |
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Soluphor® P |
| 2-Pyrrolidone used as a solvent for injectables,
mainly in the animal health. When it is used in topical preparations, it accelerates
the absorption of the active substance. |
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Solutol® HS 15 |
| Macrogol 15 hydroxystearate. Nonionic solubilizer in
paste form for use in human and veterinary parenteral preparations. |
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News |
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September 4, 2008:
Kollicoat IR:
Draft monograph for the European Pharmacopoeia
(english, deutsch) September 3, 2008:
Pharma Solutions: BASF at CPhI Worldwide
(english, deutsch) June 19, 2008:
Leading the way in respect of quality standards for pharmaceutical excipients
(english, deutsch)
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